Blood Diathesis in a Patient of Rare Blood Group ‘Bombay Phenotype’

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Identification of a rare blood group, “Bombay (Oh) phenotype,” in Bhuyan tribe of Northwestern Orissa, India

BACKGROUND Blood group serology plays a vital role in transfusion medicine. The Bombay (Oh) phenotype is characterized by the absence of A, B, and H antigens on red cells and occurs rarely, especially in tribal populations of India. AIMS AND OBJECTIVES This is a field-based random population study in the Bhuyan tribal community. The study reports three cases of the rare Bombay (Oh) phenotype ...

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Rhnull: a rare blood group phenotype.

Rhnull phenotype is a rare blood group characterized by the lack of expression of all Rh antigens (D, C, c, E and e) on the red cells. The phenotype is further classified into the regulator and amorph type based on underlying genetic defect. The clinical significance of its recognition is that such patients suffer from Rhnull syndrome associated with osmotically fragile red cells called stomato...

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Detection of a Rare Blood Group “Bombay (Oh) Phenotype” Among the Kutia Kondh Primitive Tribe of Orissa, India

Tribals constitute a major chunk of the total population of India. Out of a total 475 tribal groups in India, about 75 are primitive tribes. Kutia Kondhs of Orissa state are one of the most primitive tribal people of the country. A total of 2488 children aged 6-15 years belonging to 15 major tribes were screened for ABO and Rhesus (D) blood groups at random from various Ashram schools in eight ...

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Emergency dilatation and curettage in a patient with Bombay blood group.

Bombay blood group is a rare autosomal recessive phenotype within the ABO blood group. It represents genetically suppressed A, B and H genes. When considering such patients for transfusion, only blood of identical Bombay type can be safely transfused. We are reporting a patient having Bombay phenotypic blood, underwent emergency dilatation and curettage with active per vaginal bleeding due to r...

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Molecular basis for H blood group deficiency in Bombay (Oh) and para-Bombay individuals.

The penultimate step in the biosynthesis of the human ABO blood group oligosaccharide antigens is catalyzed by alpha-(1,2)-fucosyltransferase(s) (GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase, EC 2.4.1.69), whose expression is determined by the H and Secretor (SE) blood group loci (also known as FUT1 and FUT2, respectively). These enzymes construct Fuc alpha 1-->2Gal beta-linkag...

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ژورنال

عنوان ژورنال: Cureus

سال: 2018

ISSN: 2168-8184

DOI: 10.7759/cureus.3488